P2.07-038 Thyroid Dysfunction Arising During KEYNOTE-001 Associated with Improved Efficacy of Pembrolizumab in NSCLC Patients at UCLA
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چکیده
منابع مشابه
Evaluation of thyroid gland dysfunction in patients with alopecia areate
Introduction: Alopecia areata is a common clinical problem involving 1% of population. It is associated with many autoimmune disorders. One of the most common associations is autoimmune thyroid disease. So it seems necessary to examine the patients with alopecia areata more exactly. The main purpose of this study was to evaluate thyroid gland dysfunction in patients with alopecia areata. Mate...
متن کاملIs Subclinical Thyroid Dysfunction Associated With with Coronary Heart Disease?
Introduction: Previous cohort studies reported contradictory data on the association between subclinical thyroid dysfunction and coronary heart disease (CHD). Regarding this, the present study was conducted to illuminate this relationship. Materials and Methods: For the purpose of the study, 3,066 participants employed in a study conducted by Azizi et al. aged ≥ 20 years were subjected to thyro...
متن کاملEfficacy and Safety of Pembrolizumab in Patients Enrolled in KEYNOTE-030 in the United States: An Expanded Access Program
KEYNOTE-030 (ClinicalTrials.gov ID, NCT02083484) was a global expanded access program that allowed access to pembrolizumab, an antiprogrammed death 1 antibody, for patients with advanced melanoma before its regulatory approval. Patients with unresectable stage III/IV melanoma that progressed after standard-of-care therapy, including ipilimumab and, if BRAF mutant, a BRAF inhibitor, were eligibl...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2017
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2017.11.097